International Journal of Innovative Research in Computer and Communication Engineering

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TITLE Advancing Medical Imaging: High-Fidelity Reconstruction with SRGAN
ABSTRACT High-resolution medical imaging is essential for accurate diagnosis and clinical decision-making; however, real-world constraints such as acquisition time, patient movement, and radiation exposure often limit the achievable quality. This paper presents a two-stage Super-Resolution Generative Adversarial Network (SRGAN) designed to generate high-fidelity medical images from low-resolution inputs. The first stage reconstructs coarse high-resolution outputs, while the second stage refines anatomical textures and enhances structural fidelity. The system incorporates VGG19-based perceptual loss to preserve high-level semantic features and utilizes ResNet50 as an auxiliary feature-comparison network to ensure structural consistency across anatomical regions. A custom training strategy combining adversarial, perceptual, content, and refinement losses enables stable multi-stage optimization. Experimental observations indicate substantial improvements in perceived sharpness, edge clarity, and diagnostic detail compared to interpolation and single-stage SR models. Hypothetical quantitative evaluation suggests the model can achieve superior PSNR, SSIM, and visual realism. The proposed system demonstrates strong potential for enhancing MRI, CT, and X-ray modalities while maintaining computational feasibility. Future research may extend this approach to multimodal super-resolution, lightweight clinical deployment, and uncertainty-aware reconstructions.
AUTHOR SPOORTHI P A, DR. MALA SWADI, MADHU SHREE S, JATIN SONI Assistant Professor, Department of ECE, Dr. Ambedkar Institute of Technology, Bengaluru, India Department of ECE, Dr. Ambedkar Institute of Technology, Bengaluru, India
VOLUME 177
DOI DOI: 10.15680/IJIRCCE.2025.1312056
PDF pdf/56_Advancing Medical Imaging High-Fidelity Reconstruction with SRGAN.pdf
KEYWORDS
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