International Journal of Innovative Research in Computer and Communication Engineering
ISSN Approved Journal | Impact factor: 8.771 | ESTD: 2013 | Follows UGC CARE Journal Norms and Guidelines
| Monthly, Peer-Reviewed, Refereed, Scholarly, Multidisciplinary and Open Access Journal | High Impact Factor 8.771 (Calculated by Google Scholar and Semantic Scholar | AI-Powered Research Tool | Indexing in all Major Database & Metadata, Citation Generator | Digital Object Identifier (DOI) |
| TITLE | AI for Early Detection of Neurological Diseases: A Comprehensive Review |
|---|---|
| ABSTRACT | Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease pose considerable global health challenges, marked by progressive neuronal degeneration and functional deterioration. Conventional diagnostic methods frequently detect these conditions only subsequent to significant and irreversible cerebral damage, thereby constraining therapeutic effectiveness. This review investigates the transformative impact of artificial intelligence (AI) in facilitating the earlier identification of neurological disorders through the analysis of multimodal data sources. We combine the latest improvements in machine learning and deep learning for use in neuroimaging, speech patterns, gait analysis, retinal imaging, and clinical data integration. Recent studies show that multimodal AI models consistently do better than single-modality models. For example, they can identify Alzheimer's disease with 92.5% accuracy. New methods like explainable AI, federated learning, and anomaly detection frameworks are helping to solve important problems with model interpretability, data privacy, and finding early prodromal signatures. This review ends by pointing out the current problems and suggesting ways to move forward with putting AI-based diagnostic tools into clinical practice. |
| AUTHOR | PROF. MANJULA P, SINCHANA T, SUHASINI T R, REKHA V N, SANDEEP M, VIKASH K N, SYED SADATH H Assistant Professor, Dept. of CSE, Jain Institute of Technology, Davangere, Karnataka, India UG Students, Dept. of CSE, Jain Institute of Technology, Davangere, Karnataka, India |
| VOLUME | 184 |
| DOI | DOI: 10.15680/IJIRCCE.2026.1405017 |
| pdf/17_AI for Early Detection of Neurological Diseases A Comprehensive Review.pdf | |
| KEYWORDS | |
| References | [1] Dang, M., et al. (2026). Multimodal neuroimaging and AI integration in cognitive disorders: advances, challenges, and future directions for precision medicine. Psychoradiology, 6, kkag007. https://doi.org/10.1093/psyrad/kkag007 [2] Yu, Z., et al. (2026). Multimodal AI for Alzheimer Disease Diagnosis: Systematic Review of Datasets, Models, and Modalities. Journal of Medical Internet Research, 28, e85414. https://doi.org/10.2196/85414 [3] CogNID Study Group. (2025). AI-Driven Pipeline for Analysis and Classification of Neurodegenerative Diseases from Cognitive, Imaging, and Clinical Biomarkers. Alzheimer's & Dementia, 21(Suppl 1), e106908. https://doi.org/10.1002/alz70855_106908 [4] Soulier, T., et al. (2025). Artificial intelligence in presymptomatic neurological diseases: Bridging normal variation and prodromal signatures. Revue Neurologique, 181(9), 944-950. https://doi.org/10.1016/j.neurol.2025.07.011 [5] Jain, S., et al. (2025). Lightweight self-attention and deep gated neural network (LSA-DGNet) for multiple neurological disease detection. Computers in Biology and Chemistry, 120(Pt 1), 108621. https://doi.org/10.1016/j.compbiolchem.2025.108621 [6] Retinal biomarkers for Alzheimer's and Parkinson's diseases using advanced imaging and artificial intelligence. (2026). In Advances in Clinical Chemistry. https://doi.org/10.1016/bs.acc.2026.01.010 [7] Lohner, V., et al. (2025). Machine learning applications in vascular neuroimaging for the diagnosis and prognosis of cognitive impairment and dementia: a systematic review and meta-analysis. Alzheimer's Research & Therapy, 17. https://doi.org/10.1186/s13195-025-01815-6 [8] Singh, D., et al. (2025). An unsupervised XAI framework for dementia detection with context enrichment. Scientific Reports, 15(1). https://doi.org/10.1038/s41598-025-94689-1 [9] World Health Organization. (2020). Neurological Disorders: Public Health Challenges. Geneva: WHO Press. [10] Alzheimer's Association. (2023). Symptoms and Diagnosis of Alzheimer's Disease. Chicago: Alzheimer's Association. [11] Parkinson's Foundation. (2022). Understanding Parkinson's Disease. Miami: Parkinson's Foundation. [12] Pedregosa, F., et al. (2011). Scikit-learn: Machine Learning in Python. Journal of Machine Learning Research, 12, 2825-2830. |